A tactic that sidelines stem cells with damaged DNA, holding them as backup until later in life, may yield new ideas for cancer therapy and prevention.

Roswell Park Cancer Institute (RPCI) researcher Steven C. Pruitt, PhD, suggests that the somatic stem cells repairing and maintaining our tissues may “remember” injuries to their own DNA. DNA damage response memory (DDRM) would explain why lifelong genetic wear-and-tear seldom causes problems until middle age.

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02 Can Stem Cell Memories Of DNA Damage Delay Cancer And Age related Conditions?

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